Preheat your oven to 350°F (175°C). Grease a loaf pan.
In a large bowl, whisk together the flour, sugar, baking powder, baking soda, and salt.
Add the cranberries and orange zest to the dry ingredients and toss to combine.
In another bowl, mix together the orange juice, milk, egg, vanilla extract, and vegetable oil.
Pour the wet ingredients into the dry ingredients and stir until just combined. Do not overmix.
Pour the batter into the prepared loaf pan and smooth the top.
Bake for 60 minutes, or until a toothpick inserted into the center comes out clean.
Let the loaf cool in the pan for 10 minutes, then transfer to a wire rack to cool completely.